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Nduom EK, Gephart MH, Chheda MG, Suva ML, Amankulor N, Battiste JD, Campian JL, Dacey RG, Das S, Fecci PE, Hadjipanayis CG, Hoang KB, Jalali A, Orringer D, Patel AJ, Placantonakis D, Rodriguez A, Yang I, Yu JS, Zipfel GJ, Dunn GP, Leuthardt EC, Kim AH

Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators.
Neurosurgery. 2021;89(1):129-132 - PMID: 33862619 - DOI: 10.1093/neuros/nyab063

Bearse M, Hung YP, Krauson AJ, Bonanno L, Boyraz B, Harris CK, Helland TL, Hilburn CF, Hutchison B, Jobbagy S, Marshall MS, Shepherd DJ, Villalba JA, Delfino I, Mendez-Pena J, Chebib I, Newton-Cheh C, Stone JR

Factors associated with myocardial SARS-CoV-2 infection, myocarditis, and cardiac inflammation in patients with COVID-19.
Mod Pathol. 2021;34(7):1345-1357 - PMID: 33727695 - PMCID: PMC9813560 - DOI: 10.1038/s41379-021-00790-1

Liu N, Xu S, Yao Q, Zhu Q, Kai Y, Hsu JY, Sakon P, Pinello L, Yuan GC, Bauer DE, Orkin SH

Author Correction: Transcription factor competition at the γ-globin promoters controls hemoglobin switching.
Nat Genet. 2021;53(4):586 - PMID: 33731942 - PMCID: PMC8189157 - DOI: 10.1038/s41588-021-00834-x

Sterling RK, King WC, Khalili M, Chung RT, Sulkowski M, Jain MK, Lisker-Melman M, Ghany MG, Wong DK, Hinerman AS, Bhan AK, Wahed AS, Kleiner DE, HBV-HIV Cohort Study of the Hepatitis B Research Network

A Prospective Study Evaluating Changes in Histology, Clinical and Virologic Outcomes in HBV-HIV Co-infected Adults in North America.
Hepatology. 2021;74(3):1174-1189 - PMID: 33743541 - PMCID: PMC8597319 - DOI: 10.1002/hep.31823

Kiemes A, Davies C, Kempton MJ, Lukow PB, Bennallick C, Stone JM, Modinos G

GABA, Glutamate and Neural Activity: A Systematic Review With Meta-Analysis of Multimodal 1H-MRS-fMRI Studies.
Front Psychiatry. 2021;12:644315 - PMID: 33762983 - PMCID: PMC7982484 - DOI: 10.3389/fpsyt.2021.644315

Gazzaniga FS, Camacho DM, Wu M, Silva Palazzo MF, Dinis ALM, Grafton FN, Cartwright MJ, Super M, Kasper DL, Ingber DE

Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection.
Front Cell Infect Microbiol. 2021;11:638014 - PMID: 33777849 - PMCID: PMC7996096 - DOI: 10.3389/fcimb.2021.638014

Avants BB, Tustison NJ, Stone JR

Similarity-driven multi-view embeddings from high-dimensional biomedical data.
Nat Comput Sci. 2021;1(2):143-152 - PMID: 33796865 - PMCID: PMC8009088 - DOI: 10.1038/s43588-021-00029-8

Khalili M, Kleiner DE, King WC, Sterling RK, Ghany MG, Chung RT, Bhan AK, Rosenthal P, Lisker-Melman M, Ramachandran R, Lok AS, ; and the Hepatitis B Research Network (HBRN)

Hepatic Steatosis and Steatohepatitis in a Large North American Cohort of Adults With Chronic Hepatitis B.
Am J Gastroenterol. 2021;116(8):1686-1697 - PMID: 33840726 - PMCID: PMC8484018 - DOI: 10.14309/ajg.0000000000001257

Yerolatsitis S, Kufcsák A, Ehrlich K, Wood HAC, Fernandes S, Quinn T, Young V, Young I, Hamilton K, Akram AR, Thomson RR, Finlayson K, Dhaliwal K, Stone JM

Sub millimetre flexible fibre probe for background and fluorescence free Raman spectroscopy.
J Biophotonics. 2021;14(10):e202000488 - PMID: 33855811 - DOI: 10.1002/jbio.202000488

Vinjamur DS, Yao Q, Cole MA, McGuckin C, Ren C, Zeng J, Hossain M, Luk K, Wolfe SA, Pinello L, Bauer DE

ZNF410 represses fetal globin by singular control of CHD4.
Nat Genet. 2021;53(5):719-728 - PMID: 33859416 - PMCID: PMC8180380 - DOI: 10.1038/s41588-021-00843-w

Delorey TM, Ziegler CGK, Heimberg G, Normand R, Yang Y, Segerstolpe A, Abbondanza D, Fleming SJ, Subramanian A, Montoro DT, Jagadeesh KA, Dey KK, Sen P, Slyper M, Pita-Juárez YH, Phillips D, Bloom-Ackerman Z, Barkas N, Ganna A, Gomez J, Normandin E, Naderi P, Popov YV, Raju SS, Niezen S, Tsai LT, Siddle KJ, Sud M, Tran VM, Vellarikkal SK, Amir-Zilberstein L, Atri DS, Beechem J, Brook OR, Chen J, Divakar P, Dorceus P, Engreitz JM, Essene A, Fitzgerald DM, Fropf R, Gazal S, Gould J, Grzyb J, Harvey T, Hecht J, Hether T, Jane-Valbuena J, Leney-Greene M, Ma H, McCabe C, McLoughlin DE, Miller EM, Muus C, Niemi M, Padera R, Pan L, Pant D, Pe'er C, Pfiffner-Borges J, Pinto CJ, Plaisted J, Reeves J, Ross M, Rudy M, Rueckert EH, Siciliano M, Sturm A, Todres E, Waghray A, Warren S, Zhang S, Zollinger DR, Cosimi L, Gupta RM, Hacohen N, Hide W, Price AL, Rajagopal J, Tata PR, Riedel S, Szabo G, Tickle TL, Hung D, Sabeti PC, Novak R, Rogers R, Ingber DE, Gordon Jiang Z, Juric D, Babadi M, Farhi SL, Stone JR, Vlachos IS, Solomon IH, Ashenberg O, Porter CBM, Li B, Shalek AK, Villani AC, Rozenblatt-Rosen O, Regev A

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2.
bioRxiv. 2021;:ePub - PMID: 33655247 - PMCID: PMC7924267 - DOI: 10.1101/2021.02.25.430130

Merritt K, McGuire PK, Egerton A, 1H-MRS in Schizophrenia Investigators, Aleman A, Block W, Bloemen OJN, Borgan F, Bustillo JR, Capizzano AA, Coughlin JM, De la Fuente-Sandoval C, Demjaha A, Dempster K, Do KQ, Du F, Falkai P, Galinska-Skok B, Gallinat J, Gasparovic C, Ginestet CE, Goto N, Graff-Guerrero A, Ho BC, Howes OD, Jauhar S, Jeon P, Kato T, Kaufmann CA, Kegeles LS, Keshavan M, Kim SY, Kunugi H, Lauriello J, Liemburg EJ, Mcilwain ME, Modinos G, Mouchlianitis ED, Nakamura J, Nenadic I, Öngür D, Ota M, Palaniyappan L, Pantelis C, Plitman E, Posporelis S, Purdon SE, Reichenbach JR, Renshaw PF, Russell BR, Sawa A, Schaefer M, Shungu DC, Smesny S, Stanley JA, Stone JM, Szulc A, Taylor R, Thakkar K, Théberge J, Tibbo PG, van Amelsvoort T, Walecki J, Williamson PC, Wood SJ, Xin L, Yamasue H

Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data.
JAMA Psychiatry. 2021;78(6):667-681 - PMID: 33881460 - PMCID: PMC8060889 - DOI: 10.1001/jamapsychiatry.2021.0380

Buja LM, Stone JR

A novel coronavirus meets the cardiovascular system: Society for Cardiovascular Pathology Symposium 2021.
Cardiovasc Pathol. 2021;53:107336 - PMID: 33895311 - PMCID: PMC8062417 - DOI: 10.1016/j.carpath.2021.107336

Tustison NJ, Cook PA, Holbrook AJ, Johnson HJ, Muschelli J, Devenyi GA, Duda JT, Das SR, Cullen NC, Gillen DL, Yassa MA, Stone JR, Gee JC, Avants BB

The ANTsX ecosystem for quantitative biological and medical imaging.
Sci Rep. 2021;11(1):9068 - PMID: 33907199 - PMCID: PMC8079440 - DOI: 10.1038/s41598-021-87564-6

Delorey TM, Ziegler CGK, Heimberg G, Normand R, Yang Y, Segerstolpe Å, Abbondanza D, Fleming SJ, Subramanian A, Montoro DT, Jagadeesh KA, Dey KK, Sen P, Slyper M, Pita-Juárez YH, Phillips D, Biermann J, Bloom-Ackermann Z, Barkas N, Ganna A, Gomez J, Melms JC, Katsyv I, Normandin E, Naderi P, Popov YV, Raju SS, Niezen S, Tsai LT, Siddle KJ, Sud M, Tran VM, Vellarikkal SK, Wang Y, Amir-Zilberstein L, Atri DS, Beechem J, Brook OR, Chen J, Divakar P, Dorceus P, Engreitz JM, Essene A, Fitzgerald DM, Fropf R, Gazal S, Gould J, Grzyb J, Harvey T, Hecht J, Hether T, Jané-Valbuena J, Leney-Greene M, Ma H, McCabe C, McLoughlin DE, Miller EM, Muus C, Niemi M, Padera R, Pan L, Pant D, Pe'er C, Pfiffner-Borges J, Pinto CJ, Plaisted J, Reeves J, Ross M, Rudy M, Rueckert EH, Siciliano M, Sturm A, Todres E, Waghray A, Warren S, Zhang S, Zollinger DR, Cosimi L, Gupta RM, Hacohen N, Hibshoosh H, Hide W, Price AL, Rajagopal J, Tata PR, Riedel S, Szabo G, Tickle TL, Ellinor PT, Hung D, Sabeti PC, Novak R, Rogers R, Ingber DE, Jiang ZG, Juric D, Babadi M, Farhi SL, Izar B, Stone JR, Vlachos IS, Solomon IH, Ashenberg O, Porter CBM, Li B, Shalek AK, Villani AC, Rozenblatt-Rosen O, Regev A

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.
Nature. 2021;595(7865):107-113 - PMID: 33915569 - PMCID: PMC8919505 - DOI: 10.1038/s41586-021-03570-8

Pacenta HL, Allen-Rhoades W, Langenau D, Houghton PJ, Keller C, Heske CM, Deel MD, Linardic CM, Shern JF, Stewart E, Turpin B, Harrison DJ, Khan J, Mascarenhas L, Skapek SX, Meyer WH, Hawkins DS, Chen EY, Amatruda JF, Hingorani P, Laetsch TW

Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force.
J Clin Med. 2021;10(7):ePub - PMID: 33915882 - PMCID: PMC8037615 - DOI: 10.3390/jcm10071416

Petri K, Zhang W, Ma J, Schmidts A, Lee H, Horng JE, Kim DY, Kurt IC, Clement K, Hsu JY, Pinello L, Maus MV, Joung JK, Yeh JJ

CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells.
Nat Biotechnol. 2021;40(2):189-193 - PMID: 33927418 - PMCID: PMC8553808 - DOI: 10.1038/s41587-021-00901-y

Modinos G, Richter A, Egerton A, Bonoldi I, Azis M, Antoniades M, Bossong M, Crossley N, Perez J, Stone JM, Veronese M, Zelaya F, Grace AA, Howes OD, Allen P, McGuire P

Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes.
Neuropsychopharmacology. 2021;46(8):1468-1474 - PMID: 33941857 - PMCID: PMC8209204 - DOI: 10.1038/s41386-021-01019-0

Giblin W, Bringman-Rodenbarger L, Guo AH, Kumar S, Monovich AC, Mostafa AM, Skinner ME, Azar M, Mady AS, Chung CH, Kadambi N, Melong KA, Lee HJ, Zhang L, Sajjakulnukit P, Trefely S, Varner EL, Iyer S, Wang M, Wilmott JS, Soyer HP, Sturm RA, Pritchard AL, Andea AA, Scolyer RA, Stark MS, Scott DA, Fullen DR, Bosenberg MW, Chandrasekaran S, Nikolovska-Coleska Z, Verhaegen ME, Snyder NW, Rivera MN, Osterman AL, Lyssiotis CA, Lombard DB

The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics.
J Clin Invest. 2021;131(12):ePub - PMID: 33945506 - PMCID: PMC8203465 - DOI: 10.1172/JCI138926

Harris CK, Hung YP, Nielsen GP, Stone JR, Ferry JA

Bone Marrow and Peripheral Blood Findings in Patients Infected by SARS-CoV-2.
Am J Clin Pathol. 2021;155(5):627-637 - PMID: 33502434 - PMCID: PMC7929437 - DOI: 10.1093/ajcp/aqaa274

Avants BB, Tustison NJ, Stone JR

Publisher Correction: Similarity-driven multi-view embeddings from high-dimensional biomedical data.
Nat Comput Sci. 2021;1(3):239 - PMID: 38183202 - DOI: 10.1038/s43588-021-00049-4

Massoth LR, Desai N, Szabolcs A, Harris CK, Neyaz A, Crotty R, Chebib I, Rivera MN, Sholl LM, Stone JR, Ting DT, Deshpande V

Comparison of RNA In Situ Hybridization and Immunohistochemistry Techniques for the Detection and Localization of SARS-CoV-2 in Human Tissues.
Am J Surg Pathol. 2021;45(1):14-24 - PMID: 32826529 - DOI: 10.1097/PAS.0000000000001563

Rodriguez-Lopez J, Wright CD, Stone JR, Farber H

When Imaging in Chronic Thromboembolic Pulmonary Hypertension Is Not Enough.
Am J Respir Crit Care Med. 2021;203(2):e3-e4 - PMID: 33026826 - DOI: 10.1164/rccm.202003-0785IM

Mansouri S, Suppiah S, Mamatjan Y, Paganini I, Liu JC, Karimi S, Patil V, Nassiri F, Singh O, Sundaravadanam Y, Rath P, Sestini R, Gensini F, Agnihotri S, Blakeley J, Ostrow K, Largaespada D, Plotkin SR, Stemmer-Rachamimov A, Ferrer MM, Pugh TJ, Aldape KD, Papi L, Zadeh G

Correction to: Epigenomic, genomic, and transcriptomic landscape of schwannomatosis.
Acta Neuropathol. 2021;141(1):117 - PMID: 33112994 - PMCID: PMC7852885 - DOI: 10.1007/s00401-020-02241-8

Goreshnik A, Serling-Boyd N, Theodore M, Champion S, Stemmer-Rachamimov A, Sykes DB

A case of antisynthetase syndrome with thrombotic thrombocytopenic purpura.
Rheumatology (Oxford). 2021;60(4):e143-e145 - PMID: 33221867 - PMCID: PMC8023985 - DOI: 10.1093/rheumatology/keaa717

Natsumeda M, Miyahara H, Yoshimura J, Nakata S, Nozawa T, Ito J, Kanemaru Y, Watanabe J, Tsukamoto Y, Okada M, Oishi M, Hirato J, Wataya T, Ahsan S, Tateishi K, Yamamoto T, Rodriguez FJ, Takahashi H, Hovestadt V, Suva ML, Taylor MD, Eberhart CG, Fujii Y, Kakita A

GLI3 Is Associated With Neuronal Differentiation in SHH-Activated and WNT-Activated Medulloblastoma.
J Neuropathol Exp Neurol. 2021;80(2):129-136 - PMID: 33249504 - DOI: 10.1093/jnen/nlaa141

McQueen G, Sendt KV, Gillespie A, Avila A, Lally J, Vallianatou K, Chang N, Ferreira D, Borgan F, Howes OD, Barker GJ, Lythgoe DJ, Stone JM, McGuire P, MacCabe JH, Egerton A

Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia.
Schizophr Bull. 2021;47(3):662-671 - PMID: 33398325 - PMCID: PMC8084451 - DOI: 10.1093/schbul/sbaa156

Jerby-Arnon L, Neftel C, Shore ME, Weisman HR, Mathewson ND, McBride MJ, Haas B, Izar B, Volorio A, Boulay G, Cironi L, Richman AR, Broye LC, Gurski JM, Luo CC, Mylvaganam R, Nguyen L, Mei S, Melms JC, Georgescu C, Cohen O, Buendia-Buendia JE, Segerstolpe A, Sud M, Cuoco MS, Labes D, Gritsch S, Zollinger DR, Ortogero N, Beechem JM, Petur Nielsen G, Chebib I, Nguyen-Ngoc T, Montemurro M, Cote GM, Choy E, Letovanec I, Cherix S, Wagle N, Sorger PK, Haynes AB, Mullen JT, Stamenkovic I, Rivera MN, Kadoch C, Wucherpfennig KW, Rozenblatt-Rosen O, Suvà ML, Riggi N, Regev A

Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma.
Nat Med. 2021;27(2):289-300 - PMID: 33495604 - PMCID: PMC8817899 - DOI: 10.1038/s41591-020-01212-6

Haran FJ, Zampieri C, Wassermann EM, Polejaeva E, Dell KC, LoPresti ML, Stone JR, Ahlers ST, Carr W

Chronic Effects of Breaching Blast Exposure on Sensory Organization and Postural Limits of Stability.
J Occup Environ Med. 2021;63(11):944-950 - PMID: 33990528 - PMCID: PMC8570990 - DOI: 10.1097/JOM.0000000000002266

Rao S, Yao Y, Soares de Brito J, Yao Q, Shen AH, Watkinson RE, Kennedy AL, Coyne S, Ren C, Zeng J, Serbin AV, Studer S, Ballotti K, Harris CE, Luk K, Stevens CS, Armant M, Pinello L, Wolfe SA, Chiarle R, Shimamura A, Lee B, Newburger PE, Bauer DE

Dissecting ELANE neutropenia pathogenicity by human HSC gene editing.
Cell Stem Cell. 2021;28(5):833-845.e5 - PMID: 33513358 - PMCID: PMC8106646 - DOI: 10.1016/j.stem.2020.12.015

Cheah PS, Prabhakar S, Yellen D, Beauchamp RL, Zhang X, Kasamatsu S, Bronson RT, Thiele EA, Kwiatkowski DJ, Stemmer-Rachamimov A, György B, Ling KH, Kaneki M, Tannous BA, Ramesh V, Maguire CA, Breakefield XO

Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin.
Sci Adv. 2021;7(2):ePub - PMID: 33523984 - PMCID: PMC7793581 - DOI: 10.1126/sciadv.abb1703

Yao Q, Ferragina P, Reshef Y, Lettre G, Bauer DE, Pinello L

Motif-Raptor: A Cell Type-Specific and Transcription Factor Centric Approach for Post-GWAS Prioritization of Causal Regulators.
Bioinformatics. 2021;37(15):2103-2111 - PMID: 33532840 - PMCID: PMC11025460 - DOI: 10.1093/bioinformatics/btab072

Walton RT, Hsu JY, Joung JK, Kleinstiver BP

Scalable characterization of the PAM requirements of CRISPR-Cas enzymes using HT-PAMDA.
Nat Protoc. 2021;16(3):1511-1547 - PMID: 33547443 - PMCID: PMC8063866 - DOI: 10.1038/s41596-020-00465-2

Jelen LA, Stone JM

Ketamine for depression.
Int Rev Psychiatry. 2021;33(3):207-228 - PMID: 33569971 - DOI: 10.1080/09540261.2020.1854194

Annas GJ, Beisel CL, Clement K, Crisanti A, Francis S, Galardini M, Galizi R, Grünewald J, Immobile G, Khalil AS, Müller R, Pattanayak V, Petri K, Paul L, Pinello L, Simoni A, Taxiarchi C, Joung JK

A Code of Ethics for Gene Drive Research.
CRISPR J. 2021;4(1):19-24 - PMID: 33571044 - PMCID: PMC7898401 - DOI: 10.1089/crispr.2020.0096

Hsu JY, Grünewald J, Szalay R, Shih J, Anzalone AV, Lam KC, Shen MW, Petri K, Liu DR, Joung JK, Pinello L

PrimeDesign software for rapid and simplified design of prime editing guide RNAs.
Nat Commun. 2021;12(1):1034 - PMID: 33589617 - PMCID: PMC7884779 - DOI: 10.1038/s41467-021-21337-7

Liu N, Xu S, Yao Q, Zhu Q, Kai Y, Hsu JY, Sakon P, Pinello L, Yuan GC, Bauer DE, Orkin SH

Transcription factor competition at the γ-globin promoters controls hemoglobin switching.
Nat Genet. 2021;53(4):511-520 - PMID: 33649594 - PMCID: PMC8038971 - DOI: 10.1038/s41588-021-00798-y

Kiemes A, Gomes FV, Cash D, Uliana DL, Simmons C, Singh N, Vernon AC, Turkheimer F, Davies C, Stone JM, Grace AA, Modinos G

GABAA and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia.
Neuropsychopharmacology. 2021;47(3):687-695 - PMID: 34743200 - PMCID: PMC8782908 - DOI: 10.1038/s41386-021-01213-0

Coates JT, Sun S, Leshchiner I, Thimmiah N, Martin EE, McLoughlin D, Danysh BP, Slowik K, Jacobs RA, Rhrissorrakrai K, Utro F, Levovitz C, Denault E, Walmsley CS, Kambadakone A, Stone JR, Isakoff SJ, Parida L, Juric D, Getz G, Bardia A, Ellisen LW

Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer.
Cancer Discov. 2021;11(10):2436-2445 - PMID: 34404686 - PMCID: PMC8495771 - DOI: 10.1158/2159-8290.CD-21-0702

Yan C, Yang Q, Zhang S, Millar DG, Alpert EJ, Do D, Veloso A, Brunson DC, Drapkin BJ, Stanzione M, Scarfò I, Moore JC, Iyer S, Qin Q, Wei Y, McCarthy KM, Rawls JF, Dyson NJ, Cobbold M, Maus MV, Langenau DM

Single-cell imaging of T cell immunotherapy responses in vivo.
J Exp Med. 2021;218(10):ePub - PMID: 34415995 - PMCID: PMC8383813 - DOI: 10.1084/jem.20210314

Firdous S, Abid R, Nawaz Z, Bukhari F, Anwer A, Cheng LL, Sadaf S

Dysregulated Alanine as a Potential Predictive Marker of Glioma-An Insight from Untargeted HRMAS-NMR and Machine Learning Data.
Metabolites. 2021;11(8):ePub - PMID: 34436448 - PMCID: PMC8402070 - DOI: 10.3390/metabo11080507

Nikolova VL, Smith MRB, Hall LJ, Cleare AJ, Stone JM, Young AH

Perturbations in Gut Microbiota Composition in Psychiatric Disorders: A Review and Meta-analysis.
JAMA Psychiatry. 2021;78(12):1343-1354 - PMID: 34524405 - PMCID: PMC8444066 - DOI: 10.1001/jamapsychiatry.2021.2573

Tognon M, Bonnici V, Garrison E, Giugno R, Pinello L

GRAFIMO: Variant and haplotype aware motif scanning on pangenome graphs.
PLoS Comput Biol. 2021;17(9):e1009444 - PMID: 34570769 - PMCID: PMC8519448 - DOI: 10.1371/journal.pcbi.1009444

Edwards KA, Greer K, Leete J, Lai C, Devoto C, Qu BX, Yarnell AM, Polejaeva E, Dell KC, LoPresti ML, Walker P, Wassermann EM, Carr W, Stone JR, Ahlers ST, Vorn R, Martin C, Gill JM

Neuronally-derived tau is increased in experienced breachers and is associated with neurobehavioral symptoms.
Sci Rep. 2021;11(1):19527 - PMID: 34593828 - PMCID: PMC8484560 - DOI: 10.1038/s41598-021-97913-0

Hu H, Piotrowska Z, Hare PJ, Chen H, Mulvey HE, Mayfield A, Noeen S, Kattermann K, Greenberg M, Williams A, Riley AK, Wilson JJ, Mao YQ, Huang RP, Banwait MK, Ho J, Crowther GS, Hariri LP, Heist RS, Kodack DP, Pinello L, Shaw AT, Mino-Kenudson M, Hata AN, Sequist LV, Benes CH, Niederst MJ, Engelman JA

Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
Cancer Cell. 2021;39(11):1531-1547.e10 - PMID: 34624218 - PMCID: PMC8578451 - DOI: 10.1016/j.ccell.2021.09.003

Scheid JF, Rosenbaum MW, Przybyszewski EM, Krishnan K, Forcione DG, Iafrate AJ, Staller KD, Misdraji J, Lennerz JK, Pitman MB, Pratt DS

Next-generation sequencing in the evaluation of biliary strictures in patients with primary sclerosing cholangitis.
Cancer Cytopathol. 2021;130(3):215-230 - PMID: 34726838 - DOI: 10.1002/cncy.22528

Nunes R, Sella T, Treuner K, Atkinson JM, Wong J, Zhang Y, Exman P, Dabbs D, Richardson AL, Schnabel CA, Sgroi DC, Oesterreich S, Cimino-Mathews A, Metzger O

Prognostic Utility of Breast Cancer Index to Stratify Distant Recurrence Risk in Invasive Lobular Carcinoma.
Clin Cancer Res. 2021;27(20):5688-5696 - PMID: 34376532 - PMCID: PMC9401569 - DOI: 10.1158/1078-0432.CCR-21-0733

Malinin NL, Lee G, Lazzarotto CR, Li Y, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Iafrate AJ, Le LP, Aryee MJ, Joung JK, Tsai SQ

Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq.
Nat Protoc. 2021;16(12):5592-5615 - PMID: 34773119 - PMCID: PMC9331158 - DOI: 10.1038/s41596-021-00626-x

Stein DF, Chen H, Vinyard ME, Qin Q, Combs RD, Zhang Q, Pinello L

singlecellVR: Interactive Visualization of Single-Cell Data in Virtual Reality.
Front Genet. 2021;12:764170 - PMID: 34777482 - PMCID: PMC8582280 - DOI: 10.3389/fgene.2021.764170

Pirruccello JP, Chaffin MD, Chou EL, Fleming SJ, Lin H, Nekoui M, Khurshid S, Friedman SF, Bick AG, Arduini A, Weng LC, Choi SH, Akkad AD, Batra P, Tucker NR, Hall AW, Roselli C, Benjamin EJ, Vellarikkal SK, Gupta RM, Stegmann CM, Juric D, Stone JR, Vasan RS, Ho JE, Hoffmann U, Lubitz SA, Philippakis AA, Lindsay ME, Ellinor PT

Deep learning enables genetic analysis of the human thoracic aorta.
Nat Genet. 2021;54(1):40-51 - PMID: 34837083 - PMCID: PMC8758523 - DOI: 10.1038/s41588-021-00962-4

Schult TA, Lauer MJ, Berker Y, Cardoso MR, Vandergrift LA, Habbel P, Nowak J, Taupitz M, Aryee M, Mino-Kenudson MA, Christiani DC, Cheng LL

Screening human lung cancer with predictive models of serum magnetic resonance spectroscopy metabolomics.
Proc Natl Acad Sci U S A. 2021;118(51):ePub - PMID: 34903652 - PMCID: PMC8713787 - DOI: 10.1073/pnas.2110633118

Milenko K, Yerolatsitis S, Aksnes A, Hjelme DR, Stone JM

Micro-Lensed Negative-Curvature Fibre Probe for Raman Spectroscopy.
Sensors (Basel). 2021;21(24):ePub - PMID: 34960527 - PMCID: PMC8708690 - DOI: 10.3390/s21248434

Cheng LL

High-resolution magic angle spinning NMR for intact biological specimen analysis: Initial discovery, recent developments, and future directions.
NMR Biomed. 2021;36(4):e4684 - PMID: 34962004 - DOI: 10.1002/nbm.4684

Chung RT, King WC, Ghany MG, Lisker-Melman M, Hinerman AS, Khalili M, Sulkowski M, Jain MK, Choi EK, Nalesnik MA, Bhan AK, Cloherty G, Wong DK, Sterling RK, HBV-HIV Cohort Study of the Hepatitis B Research Network

A Prospective Cohort Study of Novel Markers of Hepatitis B Virus Replication in Human Immunodeficiency Virus Coinfection.
Clin Gastroenterol Hepatol. 2021;21(1):125-135.e8 - PMID: 34973459 - PMCID: PMC9240105 - DOI: 10.1016/j.cgh.2021.12.038

Chou EL, Lino Cardenas CL, Chaffin M, Arduini AD, Juric D, Stone JR, LaMuraglia GM, Eagleton MJ, Conrad MF, Isselbacher EM, Ellinor PT, Lindsay ME

Vascular smooth muscle cell phenotype switching in carotid atherosclerosis.
JVS Vasc Sci. 2021;3:41-47 - PMID: 35128489 - PMCID: PMC8802874 - DOI: 10.1016/j.jvssci.2021.11.002

Beharry A, Gong Y, Kim JC, Hanlon KS, Nammour J, Hieber K, Eichler F, Cheng M, Stemmer-Rachamimov A, Stankovic KM, Welling DB, Ng C, Maguire CA

The AAV9 Variant Capsid AAV-F Mediates Widespread Transgene Expression in Nonhuman Primate Spinal Cord After Intrathecal Administration.
Hum Gene Ther. 2021;33(1-2):61-75 - PMID: 34128391 - PMCID: PMC8819517 - DOI: 10.1089/hum.2021.069

Wang L, Zhang Q, Qin Q, Trasanidis N, Vinyard M, Chen H, Pinello L

Current progress and potential opportunities to infer single-cell developmental trajectory and cell fate.
Curr Opin Syst Biol. 2021;26:1-11 - PMID: 33997529 - PMCID: PMC8117397 - DOI: 10.1016/j.coisb.2021.03.006

Legius E, Messiaen L, Wolkenstein P, Pancza P, Avery RA, Berman Y, Blakeley J, Babovic-Vuksanovic D, Cunha KS, Ferner R, Fisher MJ, Friedman JM, Gutmann DH, Kehrer-Sawatzki H, Korf BR, Mautner VF, Peltonen S, Rauen KA, Riccardi V, Schorry E, Stemmer-Rachamimov A, Stevenson DA, Tadini G, Ullrich NJ, Viskochil D, Wimmer K, Yohay K, International Consensus Group on Neurofibromatosis Diagnostic Criteria (I-NF-DC), Huson SM, Evans DG, Plotkin SR

Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation.
Genet Med. 2021;23(8):1506-1513 - PMID: 34012067 - PMCID: PMC8354850 - DOI: 10.1038/s41436-021-01170-5

Shepherd DJ, Miller TE, Forst DA, Jones P, Nardi V, Martinez-Lage M, Stemmer-Rachamimov A, Gonzalez RG, Iafrate AJ, Ritterhouse LL

Mosaicism for Receptor Tyrosine Kinase Activation in a Glioblastoma Involving Both PDGFRA Amplification and NTRK2 Fusion.
Oncologist. 2021;26(11):919-924 - PMID: 34041811 - PMCID: PMC8571775 - DOI: 10.1002/onco.13835

Pereira B, Chen CT, Goyal L, Walmsley C, Pinto CJ, Baiev I, Allen R, Henderson L, Saha S, Reyes S, Taylor MS, Fitzgerald DM, Broudo MW, Sahu A, Gao X, Winckler W, Brannon AR, Engelman JA, Leary R, Stone JR, Campbell CD, Juric D

Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer.
Nat Commun. 2021;12(1):3199 - PMID: 34045463 - PMCID: PMC8160338 - DOI: 10.1038/s41467-021-23394-4

Garrood WT, Kranjc N, Petri K, Kim DY, Guo JA, Hammond AM, Morianou I, Pattanayak V, Joung JK, Crisanti A, Simoni A

Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito.
Proc Natl Acad Sci U S A. 2021;118(22):ePub - PMID: 34050017 - PMCID: PMC8179207 - DOI: 10.1073/pnas.2004838117

Kukutla P, Ahmed SG, DuBreuil DM, Abdelnabi A, Cetinbas M, Fulci G, Aldikacti B, Stemmer-Rachamimov A, Plotkin SR, Wainger B, Sadreyev RI, Brenner GJ

Transcriptomic signature of painful human neurofibromatosis type 2 schwannomas.
Ann Clin Transl Neurol. 2021;8(7):1508-1514 - PMID: 34053190 - PMCID: PMC8283170 - DOI: 10.1002/acn3.51386

Chebib I, Taylor MS, Nardi V, Rivera MN, Lennerz JK, Cote GM, Choy E, Lozano Calderón SA, Raskin KA, Schwab JH, Mullen JT, Chen YE, Hung YP, Nielsen GP, Deshpande V

Clinical Utility of Anchored Multiplex Solid Fusion Assay for Diagnosis of Bone and Soft Tissue Tumors.
Am J Surg Pathol. 2021;45(8):1127-1137 - PMID: 34115673 - DOI: 10.1097/PAS.0000000000001745

Patton EE, Zon LI, Langenau DM

Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials.
Nat Rev Drug Discov. 2021;20(8):611-628 - PMID: 34117457 - PMCID: PMC9210578 - DOI: 10.1038/s41573-021-00210-8

Rivera CM, Faquin WC, Thierauf J, Afrogheh AH, Jaquinet A, Iafrate AJ, Rivera MN, Troulis MJ

Detection of EWSR1 fusions in CCOC by targeted RNA-seq.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021;134(2):240-244 - PMID: 35165059 - DOI: 10.1016/j.oooo.2021.12.127

Li K, Li T, Feng Z, Huang M, Wei L, Yan Z, Long M, Hu Q, Wang J, Liu S, Sgroi DC, Demehri S

CD8+ T cell immunity blocks the metastasis of carcinogen-exposed breast cancer.
Sci Adv. 2021;7(25):ePub - PMID: 34144976 - PMCID: PMC8213232 - DOI: 10.1126/sciadv.abd8936

Chesters RA, Pepper F, Morgan C, Cooper JD, Howes OD, Vernon AC, Stone JM

Brain volume in chronic ketamine users - relationship to sub-threshold psychotic symptoms and relevance to schizophrenia.
Psychopharmacology (Berl). 2021;239(11):3421-3429 - PMID: 34228135 - PMCID: PMC9584979 - DOI: 10.1007/s00213-021-05873-0

Wallis D, Stemmer-Rachamimov A, Adsit S, Korf B, Pichard D, Blakeley J, Sarin KY, REiNS International Collaboration

Status and Recommendations for Incorporating Biomarkers for Cutaneous Neurofibromas Into Clinical Research.
Neurology. 2021;97(7 Suppl 1):S42-S49 - PMID: 34230199 - PMCID: PMC8594001 - DOI: 10.1212/WNL.0000000000012426

Wu L, Vasilijic S, Sun Y, Chen J, Landegger LD, Zhang Y, Zhou W, Ren J, Early S, Yin Z, Ho WW, Zhang N, Gao X, Lee GY, Datta M, Sagers JE, Brown A, Muzikansky A, Stemmer-Rachamimov A, Zhang L, Plotkin SR, Jain RK, Stankovic KM, Xu L

Losartan prevents tumor-induced hearing loss and augments radiation efficacy in NF2 schwannoma rodent models.
Sci Transl Med. 2021;13(602):ePub - PMID: 34261799 - PMCID: PMC8409338 - DOI: 10.1126/scitranslmed.abd4816

Strait AM, Bridge JA, Iafrate AJ, Li MM, Xu F, Tsongalis GJ, Linos K

Mammary-type Myofibroblastoma with Leiomyomatous Differentiation: A Rare Variant with Potential Pitfalls.
Int J Surg Pathol. 2021;30(2):200-206 - PMID: 34338561 - DOI: 10.1177/10668969211031309

Yamauchi T, Miyawaki K, Semba Y, Takahashi M, Izumi Y, Nogami J, Nakao F, Sugio T, Sasaki K, Pinello L, Bauer DE, Bamba T, Akashi K, Maeda T

Targeting leukemia-specific dependence on the de novo purine synthesis pathway.
Leukemia. 2021;36(2):383-393 - PMID: 34344987 - DOI: 10.1038/s41375-021-01369-0

Tak YE, Horng JE, Perry NT, Schultz HT, Iyer S, Yao Q, Zou LS, Aryee MJ, Pinello L, Joung JK

Augmenting and directing long-range CRISPR-mediated activation in human cells.
Nat Methods. 2021;18(9):1075-1081 - PMID: 34354266 - PMCID: PMC8446310 - DOI: 10.1038/s41592-021-01224-1

Yun JH, Lee C, Liu T, Liu S, Kim EY, Xu S, Curtis JL, Pinello L, Bowler RP, Silverman EK, Hersh CP, Zhou X

Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice.
JCI Insight. 2021;6(17):ePub - PMID: 34375314 - PMCID: PMC8492352 - DOI: 10.1172/jci.insight.144575
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