Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure.
Mol Psychiatry. 2020;26(10):5940-5954 - PMID: 32094584 - PMCID: PMC7484380 - DOI: 10.1038/s41380-020-0674-z
A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models.
Leukemia. 2020;34(12):3398-3403 - PMID: 32591643 - PMCID: PMC7906429 - DOI: 10.1038/s41375-020-0938-2
SoGut: A Soft Robotic Gastric Simulator.
Soft Robot. 2020;8(3):273-283 - PMID: 32559391 - DOI: 10.1089/soro.2019.0136
Ethics and benefits of systematic screening for active tuberculosis.
Int J Tuberc Lung Dis. 2020;24(5):44-47 - PMID: 32553043 - DOI: 10.5588/ijtld.17.0888
Publisher Correction: Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Nat Biotechnol. 2020;38(7):901 - PMID: 32541959 - DOI: 10.1038/s41587-020-0587-z
Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function.
Mol Ther Nucleic Acids. 2020;21:1-12 - PMID: 32502938 - PMCID: PMC7270506 - DOI: 10.1016/j.omtn.2020.05.009
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing.
Nat Biotechnol. 2020;38(7):861-864 - PMID: 32483364 - PMCID: PMC7723518 - DOI: 10.1038/s41587-020-0535-y
Impact of ALK Rearrangement on Venous and Arterial Thrombotic Risk in NSCLC.
J Thorac Oncol. 2020;15(9):1497-1506 - PMID: 32437899 - DOI: 10.1016/j.jtho.2020.04.033
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma.
Cell Rep. 2020;31(2):107539 - PMID: 32294441 - DOI: 10.1016/j.celrep.2020.107539
Therapeutic base editing of human hematopoietic stem cells.
hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells.
Oncotarget. 2020;11(12):1051-1074 - PMID: 32256978 - PMCID: PMC7105160 - DOI: 10.18632/oncotarget.27511
Zebrafish patient avatars in cancer biology and precision cancer therapy.
Nat Rev Cancer. 2020;20(5):263-273 - PMID: 32251397 - PMCID: PMC8011456 - DOI: 10.1038/s41568-020-0252-3
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability.
Cell Rep. 2020;30(13):4567-4583.e5 - PMID: 32234488 - DOI: 10.1016/j.celrep.2019.12.053
Neural Circuitry of Novelty Salience Processing in Psychosis Risk: Association With Clinical Outcome.
Schizophr Bull. 2020;46(3):670-679 - PMID: 32227226 - PMCID: PMC7147595 - DOI: 10.1093/schbul/sbz089
Cardiovascular magnetic resonance in immune checkpoint inhibitor-associated myocarditis.
Eur Heart J. 2020;41(18):1733-1743 - PMID: 32112560 - PMCID: PMC7205467 - DOI: 10.1093/eurheartj/ehaa051
Technologies and Computational Analysis Strategies for CRISPR Applications.
Eleven grand challenges in single-cell data science.
Diagnostic Accuracy of Shear Wave Elastography as a Non-invasive Biomarker of High-Risk Non-alcoholic Steatohepatitis in Patients with Non-alcoholic Fatty Liver Disease.
Ultrasound Med Biol. 2020;46(4):972-980 - PMID: 32005510 - PMCID: PMC7034057 - DOI: 10.1016/j.ultrasmedbio.2019.12.020
Outcome of ACHD patients with non-inducible versus inducible IART undergoing cavo-tricuspid isthmus ablation: the role of empiric ablation.
J Interv Card Electrophysiol. 2020;60(1):49-56 - PMID: 31997041 - DOI: 10.1007/s10840-019-00692-y
Neural Selective Cryoneurolysis with Ice Slurry Injection in a Rat Model.
Anesthesiology. 2020;133(1):185-194 - PMID: 31977524 - PMCID: PMC7299828 - DOI: 10.1097/ALN.0000000000003124
Microbiota-targeted maternal antibodies protect neonates from enteric infection.
Nature. 2020;577(7791):543-548 - PMID: 31915378 - PMCID: PMC7362890 - DOI: 10.1038/s41586-019-1898-4
The macrophage-expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish.
J Leukoc Biol. 2020;107(3):431-443 - PMID: 31909502 - PMCID: PMC7064944 - DOI: 10.1002/JLB.1A1119-223R
CRISPRitz: rapid, high-throughput and variant-aware in silico off-target site identification for CRISPR genome editing.
Bioinformatics. 2020;36(7):2001-2008 - PMID: 31764961 - PMCID: PMC7141852 - DOI: 10.1093/bioinformatics/btz867
Robotic fluidic coupling and interrogation of multiple vascularized organ chips.
Nat Biomed Eng. 2020;4(4):407-420 - PMID: 31988458 - PMCID: PMC8057865 - DOI: 10.1038/s41551-019-0497-x
Author Correction: On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology.
Nat Biomed Eng. 2020;4(4):477 - PMID: 32051581 - DOI: 10.1038/s41551-020-0529-6
MicroRNAs organize intrinsic variation into stem cell states.
Proc Natl Acad Sci U S A. 2020;117(12):6942-6950 - PMID: 32139605 - PMCID: PMC7104302 - DOI: 10.1073/pnas.1920695117
A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance.
Timing But Not Patterns of Recurrence Is Different Between Node-negative and Node-positive Resected Pancreatic Cancer.
Ann Surg. 2020;272(2):357-365 - PMID: 32675550 - PMCID: PMC6639153 - DOI: 10.1097/SLA.0000000000003123
Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids.
Cell Syst. 2020;10(3):223-239.e9 - PMID: 32191873 - PMCID: PMC8143761 - DOI: 10.1016/j.cels.2020.02.008
Case 1-2020: An 11-Year-Old Boy with Vomiting and Weight Loss.
N Engl J Med. 2020;382(2):180-189 - PMID: 31914246 - PMCID: PMC8176458 - DOI: 10.1056/NEJMcpc1913469
Lung Histopathology in Coronavirus Disease 2019 as Compared With Severe Acute Respiratory Sydrome and H1N1 Influenza: A Systematic Review.
LGR5 in Barrett's Esophagus and its Utility in Predicting Patients at Increased Risk of Advanced Neoplasia.
Clin Transl Gastroenterol. 2020;12(1):e00272 - PMID: 33464729 - PMCID: PMC8345923 - DOI: 10.14309/ctg.0000000000000272
Hearing Loss and Irritability Reporting Without Vestibular Differences in Explosive Breaching Professionals.
Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing.
Cell Rep. 2020;33(13):108566 - PMID: 33378681 - PMCID: PMC7898263 - DOI: 10.1016/j.celrep.2020.108566
The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.
Life Sci Alliance. 2020;4(2):ePub - PMID: 33361335 - PMCID: PMC7768195 - DOI: 10.26508/lsa.202000808
Characterization and oncolytic virus targeting of FAP-expressing tumor-associated pericytes in glioblastoma.
Acta Neuropathol Commun. 2020;8(1):221 - PMID: 33308315 - PMCID: PMC7730751 - DOI: 10.1186/s40478-020-01096-0
HIF1A signaling selectively supports proliferation of breast cancer in the brain.
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection.
Robust and Scalable Learning of Complex Intrinsic Dataset Geometry via ElPiGraph.
Core crosstalk in ordered imaging fiber bundles.
Opt Lett. 2020;45(23):6490-6493 - PMID: 33258850 - DOI: 10.1364/OL.405764
PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation.
Front Cell Dev Biol. 2020;8:599472 - PMID: 33251223 - PMCID: PMC7672048 - DOI: 10.3389/fcell.2020.599472
Epigenetic Alterations in Keratinocyte Carcinoma.
J Invest Dermatol. 2020;141(5):1207-1218 - PMID: 33212152 - PMCID: PMC8068579 - DOI: 10.1016/j.jid.2020.10.018
Case 36-2020: A 72-Year-Old Woman with Dark Urine and Weakness.
N Engl J Med. 2020;383(21):2066-2076 - PMID: 33207098 - DOI: 10.1056/NEJMcpc2027077
Rising Circulating Tumor DNA As a Molecular Biomarker of Early Disease Progression in Metastatic Breast Cancer.
JCO Precis Oncol. 2020;4:1246-1262 - PMID: 35050782 - DOI: 10.1200/PO.20.00117
High throughput single-cell detection of multiplex CRISPR-edited gene modifications.
[Telemedicine: a Proxemics tool of Primary Care?].
Ig Sanita Pubbl. 2020;76(5):288-294 - PMID: 33724982
Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies.
Cell Rep. 2020;33(1):108222 - PMID: 33027665 - PMCID: PMC7646252 - DOI: 10.1016/j.celrep.2020.108222
Epigenomic, genomic, and transcriptomic landscape of schwannomatosis.
Acta Neuropathol. 2020;141(1):101-116 - PMID: 33025139 - PMCID: PMC7785562 - DOI: 10.1007/s00401-020-02230-x
A saturating mutagenesis CRISPR-Cas9-mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs.
J Biol Chem. 2020;295(47):15797-15809 - PMID: 32994224 - PMCID: PMC7681025 - DOI: 10.1074/jbc.RA120.013772
Pathological features of COVID-19-associated myocardial injury: a multicentre cardiovascular pathology study.
Eur Heart J. 2020;41(39):3827-3835 - PMID: 32968776 - PMCID: PMC7543528 - DOI: 10.1093/eurheartj/ehaa664
Functional and Structural Neuroimaging Correlates of Repetitive Low-Level Blast Exposure in Career Breachers.
J Neurotrauma. 2020;37(23):2468-2481 - PMID: 32928028 - PMCID: PMC7703399 - DOI: 10.1089/neu.2020.7141
Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources.
J Immunother Cancer. 2020;8(2):ePub - PMID: 32900862 - PMCID: PMC7477986 - DOI: 10.1136/jitc-2020-000990
Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish.
Nat Protoc. 2020;15(9):3105-3128 - PMID: 32826993 - PMCID: PMC8097243 - DOI: 10.1038/s41596-020-0372-y
Small cell transformation of ROS1 fusion-positive lung cancer resistant to ROS1 inhibition.
Temporal and Spatial Heterogeneity of Host Response to SARS-CoV-2 Pulmonary Infection.
Tepotinib Efficacy in a Patient with Non-Small Cell Lung Cancer with Brain Metastasis Harboring an HLA-DRB1-MET Gene Fusion.
Oncologist. 2020;25(11):916-920 - PMID: 32716573 - PMCID: PMC7648335 - DOI: 10.1634/theoncologist.2020-0502
CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells.
Nat Biotechnol. 2020;39(1):41-46 - PMID: 32690971 - PMCID: PMC7854778 - DOI: 10.1038/s41587-020-0609-x
Optimization of AsCas12a for combinatorial genetic screens in human cells.
Nat Biotechnol. 2020;39(1):94-104 - PMID: 32661438 - PMCID: PMC7854777 - DOI: 10.1038/s41587-020-0600-6
Case 23-2020: A 76-Year-Old Woman Who Died from Covid-19.
N Engl J Med. 2020;383(4):380-387 - PMID: 32640127 - PMCID: PMC7367503 - DOI: 10.1056/NEJMcpc2004974